Cancer and Genetics
Cancer is a genetic disorder in which the normal control of cell growth is lost. Cancer genetics is now one of the fastest expanding medical specialties. At the molecular level, cancer is caused by mutation(s) in DNA, which result in aberrant cell proliferation. Most of these mutations are acquired and occur in somatic cells. However, some people inherit mutation(s) in the germline. The mutation(s) occur in two classes of cellular genes: oncogenes and tumor suppressor genes.
African American lung cancer patients may have different response to new cancer-fighting drugs
Submitted by Staff on Wed, 10/07/2009Clinical research out of University Hospitals Case Medical Center has found that African Americans with a common form of lung cancer have a lower frequency of drug-sensitizing genetic mutations, which may impact response to new cancer-fighting drugs. Published online in the Journal of Clinical Oncology, the study by Rom Leidner, MD, and colleagues report that ethnicity plays a significant role in non-small cell lung cancer (NSCLC) genetics and more personalized treatments may be beneficial to cancer patients.
M. D. Anderson team chosen to help navigate Cancer Genome Atlas
Submitted by Staff on Wed, 10/07/2009The Cancer Genome Atlas (TCGA) will fund an effort by scientists at The University of Texas M. D. Anderson Cancer Center to siphon buckets of meaningful information from an ocean of data about the aberrant genetics that drive human cancers.
SAGE launches Genes & Cancer
Submitted by Staff on Mon, 10/05/2009SAGE announces Genes & Cancer, a monthly journal edited by Dr. Prem Reddy, founder and previous Editor-in-Chief of the prestigious and highly-ranked Oncogene.

